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Clinical Trials

RECRUITING
Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
The Cutaneous Lupus Erythematosus (CLE) database, established in 2006, is a multi-site database between the University of Pennsylvania and the Univers...
Conditions:
Cutaneous Lupus Erythematosus (CLE)
Locations:
📍 Philadelphia, Pennsylvania, United States
📍 Dallas, Texas, United States
RECRUITING
A Research Study to Evaluate the Effectiveness and Safety of Cenerimod in Subjects Suffering From Lupus
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematous in adult patients with moderate to severe...
Conditions:
Lupus Erythematosus, Systemic
Locations:
📍 La Jolla, California, United States
📍 Riverside, California, United States
📍 Coral Gables, Florida, United States
📍 Hialeah, Florida, United States
106 more locations available...
RECRUITING
A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Patients Who Have Lupus
In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in patients with systemic lupus erythematosus (SLE). The st...
Conditions:
Lupus Erythematosus, Systemic
Locations:
📍 Birmingham, Alabama, United States
📍 Glendale, Arizona, United States
📍 Los Alamitos, California, United States
📍 Whittier, California, United States
150 more locations available...
RECRUITING
The Willow LTE Study With M5049 in Patients With SCLE, DLE and/or SLE (WILLOW LTE)
The purpose of the study is to assess the long term safety and efficacy of orally administered M5049 in patients with subacute cutaneous lupus erythem...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Miami, Florida, United States
📍 Indianapolis, Indiana, United States
📍 Grand Blanc, Michigan, United States
📍 Memphis, Tennessee, United States
63 more locations available...
NOT_YET_RECRUITING
A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Lupus (SLE) or Lupus
Background: Systemic lupus erythematosus (SLE), also called lupus, is a disease that causes the body s immune system to attack healthy tissue. Lupus ...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Bethesda, Maryland, United States
RECRUITING
Subcutaneous Anifrolumab in Adult Patients With Lupus
The purpose of this study is evaluating the efficacy and safety of SC antifrolumab in adult patients with moderate -to-severe SLE despite receiving st...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Birmingham, Alabama, United States
📍 Paradise Valley, Arizona, United States
📍 Phoenix, Arizona, United States
194 more locations available...
RECRUITING
AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Lupus
AB-101 (also known as AlloNK) is an off-the shelf, allogeneic cell product made of "natural killer" cells, also called NK cells. White blood cells are...
Conditions:
Lupus Nephritis - WHO Class III Lupus Nephritis - WHO Class IV Refractory Systemic Lupus Erythematosus
Locations:
📍 Birmingham, Alabama, United States
📍 San Diego, California, United States
RECRUITING
Descartes-08 for Patients With Lupus
This is a Phase II study to assess the safety, tolerability and manufacturing feasibility of Descartes-08 CAR T-cells in patients with Systematic Lupu...
Conditions:
Systemic Lupus Erythematosus (SLE)
Locations:
📍 Oceanside, California, United States
RECRUITING
Study on Telitacicept for the Treatment of Moderately to Severely Active Lupus (REMESLE-1)
The purpose of this study is to assess the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Birmingham, Alabama, United States
📍 Huntington Park, California, United States
📍 La Mesa, California, United States
85 more locations available...
RECRUITING
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedic...
Conditions:
Age-Related Macular Degeneration Allergies Alpha-Gal Syndrome Alzheimer Disease
43 more conditions available...
Locations:
📍 Waltham, Massachusetts, United States
RECRUITING
Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Patients With Autoimmune Disease
The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection...
Conditions:
Sjögrens Disease Systemic Lupus Erythematosus Rheumatoid Arthritis
Locations:
📍 Winter Park, Florida, United States
📍 Grand Blanc, Michigan, United States
📍 Oklahoma City, Oklahoma, United States
📍 Bellaire, Texas, United States
RECRUITING
A Study to Assess the Effectiveness and Safety of BIIB059 (Litifilimab) in Patients With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy
The primary objectives of the study are to assess the efficacy of BIIB059 (litifilimab) compared with placebo in reducing skin disease activity measur...
Conditions:
Subacute Cutaneous Lupus Erythematosus Chronic Cutaneous Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Birmingham, Alabama, United States
📍 Phoenix, Arizona, United States
📍 La Jolla, California, United States
225 more locations available...
RECRUITING
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology population...
Conditions:
Juvenile Idiopathic Arthritis Systemic Lupus Erythematosus Fibromyalgia
Locations:
📍 Washington, District of Columbia, United States
RECRUITING
Study of Daxdilimab (HZN-7734) in Patients With Moderate-to-Severe Primary Discoid Lupus Erythematosus
A Phase 2, double-blind, randomized, placebo-controlled parallel-group study to assess the efficacy and safety of daxdilimab in patients with moderate...
Conditions:
Discoid Lupus Erythematosus
Locations:
📍 North Little Rock, Arkansas, United States
📍 Beverly Hills, California, United States
📍 Fremont, California, United States
📍 Santa Monica, California, United States
64 more locations available...
RECRUITING
Clarifying Misbeliefs About Hydroxychloroquine: Developing a Decision Aid for Patients With Lupus
The purpose of this research study is to collect information from lupus patients about their experience with a tool that informs patients about the be...
Conditions:
Lupus
Locations:
📍 Madison, Wisconsin, United States

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